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1.

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EB
edited by Mark A. Babizhayev, David Wan-Cheng Li, Anne Kasus-Jacobi, Lep?a ?ori?, Jorge L. Alio
出版情報: New York, NY : Springer New York : Imprint: Humana Press, 2015
シリーズ名: Oxidative Stress in Applied Basic Research and Clinical Practice ;
オンライン: http://dx.doi.org/10.1007/978-1-4939-1935-2
目次情報: 続きを見る
1 Oxidative Stress in Cornea
2 Corneal Degenerations
3 Corneal Epithelial Nuclear Ferritin and its Transporter Ferritoid Afford Unique Protection to DNA from U.V. Light and Reactive Oxygen Species
4 Excitatory Amino Acid Transporters, Xc- Antiporter, Glutamyl Transpeptidase, Glutamine Synthetase Activity and Glutathione in Human Corneal Epithelial Cells
5 Transforming Growth Factor ? β3 Regulates Cell Metabolism in Corneal Keratocytes and Fibroblasts
6 Corneal Stem Cells: a Source of Cell Renewal with Therapeutic Potential
7 New Agents for Treating Dry Eye Syndrome
8 Investigating Carcinine Transport and the Expression Profile of Transporter Genes in Human Corneal Epithelial Cells
9 Basic Review of the Oxidative Stress Role in Age-Related Cataractogenesis
10 The Human Lens: A living Biometric Indicator of Health Status and Successful Aging
11 Oxidative Stress in Lens
12 Protein Serine/Threonine Phosphatases-1 and ?2A in Lens Development and Pathogenesis
13 Proteases in Lens and Cataract
14 Photosensitized Oxidation of Lens Proteins Exposed to UVA-Visible Light at Low Oxygen Concentration: Its Effect on the Proteasome System
15 p53 Regulates Developmental Apoptosis and Gene Expression to Modulate Lens Differentiation
16 Etiology and Prevention of Cataract
17 The Effects of Lutein in Preventing Cataract Progression
18 Antioxidant Defense Network in the Lens and Benefits of Glutathione Prodrugs in Cataracts
19 Updates and Advanc es in Corneal Surgery
20 Cataract and Diabetic Retinopathy
21 Traumatic Cataract-a Review
22 Cataract in Paediatric Age Group-a Review
1 Oxidative Stress in Cornea
2 Corneal Degenerations
3 Corneal Epithelial Nuclear Ferritin and its Transporter Ferritoid Afford Unique Protection to DNA from U.V. Light and Reactive Oxygen Species
2.

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EB
edited by Martin M. Kowalewski, Paul A. Garber, Liliana Cortes-Ortiz, Bernardo Urbani, Dionisios Youlatos
出版情報: New York, NY : Springer New York : Imprint: Springer, 2015
シリーズ名: Developments in Primatology: Progress and Prospects ;
オンライン: http://dx.doi.org/10.1007/978-1-4939-1957-4
目次情報: 続きを見る
Part 1. Introduction
Chapter 1. Why is it Important to Continue Studying the Anatomy, Physiology, Sensory Ecology, and Evolution of Howler Monkeys?
Part 2. Taxonomy, Genetics, Morphology and Evolution
Chapter 2. Fossil Alouattines and the Origins of Alouatta: Craniodental Diversity and Interrelationships
Chapter 3. The Taxonomy of Howler Monkeys: Integrating Old and New Knowledge from Morphological and Genetic Studies
Chapter 4. Cytogenetics of Howler Monkeys
Chapter 5. Hybridization in Howler Monkeys: Current Understanding and Future Directions
Chapter 6. Morphology of Howler Monkeys: A Review and Quantitative Analyses
Part 3. Physiology
Chapter 7. Hematology and Serum Biochemistry in Wild Howler Monkeys
Chapter 8. Endocrinology of Howler Monkeys: Review and Directions for Future Research
Chapter 9. The Howler Monkey as a Model for Exploring Host-Gut Microbiota Interactions in Primates
Chapter 10. Ecological Determinants of Parasitism in Howler Monkeys
Part 4. Ontogeny and Sensory Ecology
Chapter 11. An Ontogenetic Framework for Alouatta: Infant Development and Evaluating
Chapter 12.The Sensory Systems of Alouatta: Evolution with an Eye to Ecology
Chapter 13. Production of Loud and Quiet Calls in Howler Monkeys
Chapter 14. Function of Loud Calls in Howler Monkeys
Part 5. Conclusions
Chapter 15. New Challenges in the Study of Howler Monkey Anatomy, Physiology, Sensory Ecology, and Evolution: Where we are and where we need to go?
Part 1. Introduction
Chapter 1. Why is it Important to Continue Studying the Anatomy, Physiology, Sensory Ecology, and Evolution of Howler Monkeys?
Part 2. Taxonomy, Genetics, Morphology and Evolution
3.

電子ブック

EB
edited by Masami Tatsuno
出版情報: New York, NY : Springer New York : Imprint: Springer, 2015
シリーズ名: Springer Series in Computational Neuroscience ; 12
オンライン: http://dx.doi.org/10.1007/978-1-4939-1969-7
目次情報: 続きを見る
Part I.? Method of Multi-Electrode Recording
Chapter 1. Techniques for Large-Scale Multiunit Recording
Chapter 2. Silicon Probe Techniques for Large-scale Multiunit Recording
Part II. Coordinated Neural Activity in Rodent Hippocampus and Associated Areas
Chapter 3. Overview of Neural Activity in the Awake and Sleeping Hippocampus
Chapter 4. Associative Reactivation of Place-Reward Information in the Hippocampal-Ventral Striatal Circuitry
Chapter 5. Hippocampal Sequences and the Cognitive Map
Chapter 6. Reorganization of Hippocampal Place-Selective Patterns During Goal-Directed Learning and Their Reactivation During Sleep
Chapter 7. Causal Relationship Between SPW-Rs and Spatial Learning and Memory
Part III. Cortical Neural Activity and Interaction with the Hippocampus
Chapter 8. Packets of Sequential Neural Activity in Sensory Cortex
Chapter 9. Coordinated Sequence Replays Between the Visual Cortex and Hippocampus
Chapter 10. Memory Consolidation, Replay, and Cortico-Hippocampal Interactions
Part IV. Memory Reactivation in Humans
Chapter 11. Memory Reactivation in Humans (Imaging Studies)
Part V. Computational Modeling of Coordinated Neural Activity
Chapter 12. Models and Theoretical Frameworks for Hippocampal and Entorhinal Cortex Function in Memory and Navigation
Chapter 13.? Information Encoding and Reconstruction by Phase Coding of Spikes
Chapter 14. Reinforcement Learning and Hippocampal Dynamics
Chapter 15. Off-line Replay and Hippocampal-Neocortical Interaction
Part I.? Method of Multi-Electrode Recording
Chapter 1. Techniques for Large-Scale Multiunit Recording
Chapter 2. Silicon Probe Techniques for Large-scale Multiunit Recording
4.

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EB
edited by Xiu-Qing Li, Danielle J. Donnelly, Thomas G. Jensen
出版情報: New York, NY : Springer New York : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-1-4939-2389-2
目次情報: 続きを見る
Drug and Gene Electrotransfer in Cancer Therapy
Targeted Porcine Genome Engineering with TALENs
Somatic Gene Therapy using Viral Vectors: theoretical and clinical implications in relation to treatment of genetic conditions in humans
Nonviral Gene Therapy ? The Challenge of Mobilizing DNA
Human Stromal Stem Cell Therapy Using Gene Modified Cells
Somatic Cell Nuclear Transfer and the Creation of Transgenic Large Animal Models
Apomixis: The Asexual Formation of Seed
Somatic Embryogenesis for Potato (Solanum tuberosum L.) Improvement
Brassica Ogu-INRA Cytoplasmic Male Sterility: An Example of Successful Plant Somatic Fusion for Hybrid Seed Production
Protoplast Technology in Genome Manipulation of Potato Through Somatic Cell Fusion
Strategic RNA Silencing for Plant Viral Resistance
Targeted Gene Mutation in Plants
Mitochondrial Genetic Manipulation
Laboratory Methods for Investigating Nuclear and Cytoplasmic Genomes and Transcriptome
Bioinformatic approaches for analysis of gene direction, chromosome base composition, mRNA polyadenylation, and protein network
Drug and Gene Electrotransfer in Cancer Therapy
Targeted Porcine Genome Engineering with TALENs
Somatic Gene Therapy using Viral Vectors: theoretical and clinical implications in relation to treatment of genetic conditions in humans
5.

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edited by Girdhar K. Pandey
出版情報: New York, NY : Springer New York : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-1-4939-2540-7
目次情報: 続きを見る
Role of Plant Mediator Complex in Stress Response
Towards understanding the transcriptional control of abiotic stress tolerance mechanisms in food legumes
Insights into the small RNA mediated networks in response to abiotic stress in plants
The Role of Long Non-coding RNAs in abiotic stress tolerance in plants
Molecular physiology of heat Stress Responses in Plants
The Omics of cold stress responses in plants
Drought stress responses and signal transduction in plants
Physiological and molecular mechanisms of flooding tolerance in plants
Salt Adaptation Mechanisms of Halophytes: Improvement of Salt Tolerance in Crop Plants
UV-B Photoreceptors, their role in photosignaling, physiological responses and abiotic stress in plants
Analysis of signaling pathways during heavy metal toxicity: A functional genomic perspective
Nitrogen and Stress
Signaling pathways in eukaryotic stress, aging and senescence: Common and distinct pathways
Designing climate smart future crops employing signal transduction components
Abiotic Stress in Crops: Candidate Genes, Osmolytes, Polyamines and Biotechnological Intervention
Abiotic stress tolerance and sustainable agriculture: A functional genomic perspective
Role of Plant Mediator Complex in Stress Response
Towards understanding the transcriptional control of abiotic stress tolerance mechanisms in food legumes
Insights into the small RNA mediated networks in response to abiotic stress in plants
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by Kewal K. Jain
出版情報: New York, NY : Springer New York : Imprint: Humana Press, 2015
オンライン: http://dx.doi.org/10.1007/978-1-4939-2553-7
目次情報: 続きを見る
Basic Aspects
Molecular Diagnostics in Personalized Medicine
Role of Biomarkers in Personalized Medicine
Pharmacogenetics
Pharmacogenomics
Pharmacoproteomics
Role of Metabolomics in Personalized Medicine
Non-genomic Factors in the Development of Personalized Medicine
Personalized Biological Therapies
Personalized Therapy of Cancer
Personalized Management of Infectious Diseases
Personalized Management of Neurological Disorders
Personalized Management of Psychiatric Disorders
Personalized Management of Cardiovascular Disorders
Personalized Management of Pulmonary Disorders
Personalized Management of Genetic Disorders
Personalized Approaches to Immune Disorders
Personalized Approaches to Miscellaneous Problems in Healthcare
Personalized Non-Pharmacological Therapies
Development of Personalized Medicine
Ethical Aspects of Personalized Medicine
Regulatory Aspects of Personalized Medicine
Economics of Personalized Medicine
Future of Personalized Medicine
Basic Aspects
Molecular Diagnostics in Personalized Medicine
Role of Biomarkers in Personalized Medicine
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edited by Feng Zhang, Holger Puchta, James G. Thomson
出版情報: New York, NY : Springer New York : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-1-4939-2556-8
目次情報: 続きを見る
Double-strand break repair and its application to genome engineering in plants
Engineering meganuclease for precise plant genome modification
High efficient genome modification by designed Zinc Finger Nuclease
Engineered TAL effector proteins:? versatile reagents for manipulating plant genomes
Oligo-mediated targeted gene editing
Gene targeting in crop species with effective selection systems
Recombinase Technology for Precise Genome Engineering
PBRM1: Developing CRISPR technology in major crop plants
Double-strand break repair and its application to genome engineering in plants
Engineering meganuclease for precise plant genome modification
High efficient genome modification by designed Zinc Finger Nuclease
8.

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by Timothy G. Townsend, Jon Powell, Pradeep Jain, Qiyong Xu, Thabet Tolaymat, Debra Reinhart
出版情報: New York, NY : Springer New York : Imprint: Springer, 2015
シリーズ名: Waste Management Principles and Practice ;
オンライン: http://dx.doi.org/10.1007/978-1-4939-2662-6
目次情報: 続きを見る
CHAPTER 1.The Landfill’s Role in Sustainable Waste Management
CHAPTER 2.Waste and Landfill Fundamentals
CHAPTER 3.? Planning for Sustainable Landfilling Practices
CHAPTER 4.State of Practice
CHAPTER 5.Landfill Constituent Relationships and Dynamics
CHAPTER 6.Moisture Supply and Conveyance
CHAPTER 7.Systems for Surface Addition of Liquids
CHAPTER 8.? Buried Vertical Systems for Liquids Addition
CHAPTER 9.Buried Horizontal Systems for Liquids Addition
CHAPTER 10.Leachate Collection and Removal Systems (LCRS)
CHAPTER 11.?Leachate Control, Storage, and Treatment
CHAPTER 12.Slope Stability
CHAPTER 13.LFG
CHAPTER 14.Landfill Air Addition
CHAPTER 15.Operations
CHAPTER 16.Tools and Techniques for Landfill Monitoring
CHAPTER 17.Final Landfill Disposition
CHAPTER 18.Economics
CHAPTER 1.The Landfill’s Role in Sustainable Waste Management
CHAPTER 2.Waste and Landfill Fundamentals
CHAPTER 3.? Planning for Sustainable Landfilling Practices
9.

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edited by Kyriacos Felekkis, Konstantinos Voskarides
出版情報: New York, NY : Springer New York : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-1-4939-3070-8
目次情報: 続きを見る
MicroRNAs' function and role in evolution
MicroRNAs and disease
piRNAs: Transposon silencing and germ line development.-Long non-coding cRNAs
Unveiling transposable elements function to enrich knowledge for human physiology and disease pathogenesis
Copy number variation in human health, disease and evolution
Mini- and micro-satellite markers in health, disease and evolution
Intron biology, focusing on group II introns, the ancestors of spliceosomal introns
Centromeres in health, disease and evolution
Structure and functions of telomeres in organismal homeostasis and disease
Proximal regulatory elements with emphasis on CpG rich regions
Genomic analysis through high-throughput sequencing
MicroRNAs' function and role in evolution
MicroRNAs and disease
piRNAs: Transposon silencing and germ line development.-Long non-coding cRNAs
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edited by K. D. Rainsford, M. C. Powanda, M. W. Whitehouse
出版情報: Basel : Springer Basel : Imprint: Springer, 2015
シリーズ名: Progress in Drug Research ; 70
オンライン: http://dx.doi.org/10.1007/978-3-0348-0927-6
目次情報: 続きを見る
Aloe vera: a Natural Healing Agent for Gastro-intestinal and Chronic Inflammatory Conditions
Chondroitin Sulphate and Glucosamine Sulphate as Potential Disease-Modifying Agents for Osteoarthritis
Probiotics as Natural Healing Agents for Gastro-intestinal Diseases and Arthritis
Therapeutic Effects of Ribonucleinate (Ribonucleotides) in Immuno-inflammatory and Arthritic Diseases
The Medicinal Properties and Phytochemistry of Plants of the Genus Terminalia (Combretaceae)
Celery Seed and Related Extracts with Anti-athritic, Anti-Ulcer and anti-Microbial Activities
Lyprinol, Lipids and other Components of Green Lipped Mussel as Anti-Arthritic and? Anti-Ulcer Agents
Zinc Compounds as Topical and Oral Anti-Arthritic and Anti-ulcer Compounds
Aloe vera: a Natural Healing Agent for Gastro-intestinal and Chronic Inflammatory Conditions
Chondroitin Sulphate and Glucosamine Sulphate as Potential Disease-Modifying Agents for Osteoarthritis
Probiotics as Natural Healing Agents for Gastro-intestinal Diseases and Arthritis
11.

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by Christoph Richter
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-07422-1
目次情報: 続きを見る
Part I: Wood, a Truly Remarkable Material
The Anatomical Structure of Wood
Wood Characteristic or Defect?
General Factors Leading to the Formation of Wood Characteristics of the Tree
Part II: Wood Characteristics Overview
Overview of the Main Wood Characteristics
Part III: Description of the Wood Characteristics
Wood Characteristics Inherent in a Tree´s Natural Growth
Biotically Induced Wood Characteristics
Abiotically Induced Wood Characteristics
Overview of Cracks Shake Forms and Causes.
Part I: Wood, a Truly Remarkable Material
The Anatomical Structure of Wood
Wood Characteristic or Defect?
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edited by Panayiotis Vlamos, Athanasios Alexiou
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Advances in Experimental Medicine and Biology ; 820
オンライン: http://dx.doi.org/10.1007/978-3-319-09012-2
目次情報: 続きを見る
Bioinformatics, Mathematical & Computational Medicine
Systems Biology of Ageing and Other New Technologies
Nanotechnology in Neuroscience and Neurosurgery
Nervous System-Cognition and Ageing
Neuroinformatics
Health Informatics.?
Bioinformatics, Mathematical & Computational Medicine
Systems Biology of Ageing and Other New Technologies
Nanotechnology in Neuroscience and Neurosurgery
13.

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edited by Apostolos Pappas
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-09943-9
目次情報: 続きを見る
1.?Editor’s Introduction: Skin lipids (epidermal, sebaceous, subcutaneous)
2.?Skin basics, structure and function
3. Skin barrier, structure and properties
4.?Lipid oxidation and mediators in skin
5.?Skin Ceramides
6. Cholesterol synthesis in epidermis
7. Transcriptional factors and epidermal differentiation
8. The brain of the skin: sebaceous gland
9.?Sebaceous lipids
10.?Sapienic acid and sebum specific fatty acid metabolism
11. Wax Esters chemistry and synthesis
12.?Squalene chemistry and biology
13.?Adipose tissue and fat cell biology
14.?acial subcutaneous tissue
15.?Monounsaturated fatty acid synthesis genes and skin/hair
16. Triglyceride synthesis genes and skin/hair
17.?Lipoxygenase and skin
18.?PPAR gamma receptor, skin lipids and hair
19. Mineral oils in skincare
20.?Lipophilic antioxidants and skincare
21.?Glycerol, Fatty alcohols, acids and esters in cosmetics
22.?Vegetable and natural oils in cosmetics
23.?Acne and lipid pathways
24.?Atopic dermatitis and lipids.??? ?
1.?Editor’s Introduction: Skin lipids (epidermal, sebaceous, subcutaneous)
2.?Skin basics, structure and function
3. Skin barrier, structure and properties
14.

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edited by Mieczyslaw Pokorski
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Advances in Experimental Medicine and Biology ; 837
オンライン: http://dx.doi.org/10.1007/978-3-319-10006-7
目次情報: 続きを見る
Inherited Disorders of Brain Neurotransmitters: Pathogenesis and Diagnostic Approach
Inhibition of Peripheral Dopamine Metabolism and the Ventilatory Response to Hypoxia in the Rat
Adaptation of Olfactory Threshold at High Altitude
Guanosine Protects Glial Cells against 6-Hydroxydopamine Toxicity
Chemoresponsiveness and Breath Physiology in Anosmia
Cognitive Functioning of the Prelingually Deaf Adults
Hypoxia-Related Brain Dysfunction in Forensic Medicine
Does Health Status Influence Acceptance of Illness in Patients with Chronic Respiratory Diseases?
Inherited Disorders of Brain Neurotransmitters: Pathogenesis and Diagnostic Approach
Inhibition of Peripheral Dopamine Metabolism and the Ventilatory Response to Hypoxia in the Rat
Adaptation of Olfactory Threshold at High Altitude
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edited by Mieczyslaw Pokorski
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Advances in Experimental Medicine and Biology ; 839
オンライン: http://dx.doi.org/10.1007/978-3-319-10012-8
目次情報: 続きを見る
Inhaled Corticosteroids Increase Siglec-5/14 Expression in Sputum Cells of COPD Patients
Tregs and HLA-DR Expression in Sputum Cells of COPD Patients Treated with Tiotropium and Formoterol
Inhalation of Macrolides: A Novel Approach to Treatment of Pulmonary Infections
Influence of Denture Plaque Biofilm on Oral Mucosal Membrane in Patients with Chronic Obstructive Pulmonary Disease
Biophysical Activity of Animal-Derived Exogenous Surfactants Mixed with Rifampicin
Organic Changes in the Central Nervous System in Children on Chronic Inhaled Corticosteroid Therapy
Stem Cell Experiments Moves into Clinic: New Hope for Children with Bronchopulmonary Dysplasia
Soluble Ligand CD40 and Uric Acid as Markers of Atheromatosis in Patients with Obstructive Sleep Apnea
Carotid Artery Intima-Media Thickness in Hypertensive Patients with Obstructive Sleep Apnea
Inhaled Corticosteroids Increase Siglec-5/14 Expression in Sputum Cells of COPD Patients
Tregs and HLA-DR Expression in Sputum Cells of COPD Patients Treated with Tiotropium and Formoterol
Inhalation of Macrolides: A Novel Approach to Treatment of Pulmonary Infections
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edited by Michael B. A. Oldstone, Richard W. Compans
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Current Topics in Microbiology and Immunology ; 386
オンライン: http://dx.doi.org/10.1007/978-3-319-11158-2
目次情報: 続きを見る
The role of cytokine responses during influenza virus pathogenesis and potential therapeutic options
Innate immune sensing and response to influenza
The NS1 protein: a multitasking virulence factor
Role of NK cells in influenza infection
Host detection and the stealthy phenotype in influenza virus infection
Inactivated and adjuvanted influenza vaccines
Live attenuated influenza vaccine
Design of alternative live attenuated influenza virus vaccines
Rapid production of synthetic influenza vaccines
Influenza neuraminidase as a vaccine antigen
Advances in universal influenza virus vaccine design and antibody mediated therapies based on conserved regions of the hemagglutinin
Structural characterization of epitopes recognized by broadly cross-reactive antibodies
Skin immunization with influenza vaccines
Mucosal immunization and adjuvants
B cell responses to infection and vaccination
Memory CD4 T cells in influenza
The effector T cell response to influenza infection
Antiviral Effects of Inhibiting Host Gene Expression. ?
The role of cytokine responses during influenza virus pathogenesis and potential therapeutic options
Innate immune sensing and response to influenza
The NS1 protein: a multitasking virulence factor
17.

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edited by Antonio Guglietta
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Milestones in Drug Therapy ;
オンライン: http://dx.doi.org/10.1007/978-3-319-11514-6
目次情報: 続きを見る
An overview of sleep physiology and sleep regulation
Neuronal networks regulating sleep and arousal: effect of drugs
Classification of sleep disorders
Development of new therapeutical agents for treatment of insomnia and other sleep disorders
Low dose doxepin for insomnia
Lorediplon: a new GABAa modulator drug for treatment of insomnia
Zolpidem sublingual formulations
Eszopiclone: review and clinical applications in chronic and co-morbid insomnia
Orexin/hypocretin antagonists in insomnia: from bench to clinic
Modafinil and armodafinil
Sodium oxybate (XyremR): a new and effective treatment for narcolepsy with cataplexy
Cell therapy to treat narcolepsy
Tasimelteon
The past, present and future of drug development and treatment in sleep disorders
An overview of sleep physiology and sleep regulation
Neuronal networks regulating sleep and arousal: effect of drugs
Classification of sleep disorders
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by Vladimir S. Saakov, Alexander I. Krivchenko, Eugene V. Rozengart, Irina G. Danilova
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-11596-2
目次情報: 続きを見る
Introduction. Development of the methodological base, disputes, conclusions
Successes of the pulse amplitude modulated fluorescence application
Methodological approaches in our experimental work
Application of Derivative Spectrophotometry in Comparative Biochemical Studies
The Range of DHSO Application in Experiments with Pigments of Plants and Animals
Conclusion
Introduction. Development of the methodological base, disputes, conclusions
Successes of the pulse amplitude modulated fluorescence application
Methodological approaches in our experimental work
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edited by Gregory Lloyd Blatch, Adrienne Lesley Edkins
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Subcellular Biochemistry ; 78
オンライン: http://dx.doi.org/10.1007/978-3-319-11731-7
目次情報: 続きを見る
Preface
List of Contributors- About the Editors- GrpE, Hsp110/Grp170, HspBP1/Sil1 and BAG domain proteins: Nucleotide exchange factors for Hsp70 molecular chaperones
Functions of the Hsp90-Binding FKBP Immunophilins
Hsp70/Hsp90 organising protein (Hop): beyond interactions with chaperones and prion proteins
Specification of Hsp70 function by Type I and Type II Hsp40
Cdc37 as a Co-chaperone to Hsp90
p23 and Aha1- UCS proteins: chaperones for myosin and co-chaperones for Hsp90
Chaperonin - Co-chaperonin Interactions
Co-chaperones of the mammalian endoplasmic reticulum
The evolution and function of co-chaperones in mitochondria
CHIP: a co-chaperone for degradation by the proteasome
The role of HSP70 and its co-chaperones in protein misfolding, aggregation and disease
Index
Preface
List of Contributors- About the Editors- GrpE, Hsp110/Grp170, HspBP1/Sil1 and BAG domain proteins: Nucleotide exchange factors for Hsp70 molecular chaperones
Functions of the Hsp90-Binding FKBP Immunophilins
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edited by Chris Maxwell, Cal Roskelley
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Cancer Metastasis - Biology and Treatment ; 20
オンライン: http://dx.doi.org/10.1007/978-3-319-12136-9
目次情報: 続きを見る
Preface
Cancer Metastasis: Tracking and Attacking a Moving Target
The generation, detection, and prevention of genomic instability during cancer progression and metastasis
DNA damage response pathways in cancer predisposition and progression
Mathematical modeling for DNA repair, carcinogenesis and cancer detection
Animal models of metastasis
Microenvironmental Control Of Metastatic Progression
7 Mechanotransduction, metastasis and genomic instability
8 Immunomodulation and Genomic Instability
9 Synthetic Genetic Approaches in Colorectal Cancer: Exploiting and Targeting Genome Instability
Nanomedicine ? Nanoparticles in Cancer Imaging and Therapy
Index
Preface
Cancer Metastasis: Tracking and Attacking a Moving Target
The generation, detection, and prevention of genomic instability during cancer progression and metastasis
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by Florencio Pazos, Monica Chagoyen
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-12727-9
目次情報:
Sequences
Structures
Systems
Sequences
Structures
Systems
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edited by Jose A. Torres, Sol Bobst
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-12751-4
目次情報: 続きを見る
Introduction
Hazard Identification
Dose-Response
Exposure Assessment
Risk Characterization for Human Health Risk Assessments
Risk Assessment Strategies and Techniques for Combined Exposures
Use of Epidemiology in Risk Assessment
Emerging Issues in Risk Assessment
Risk Assessment in the European Union (EU)
Brief Survey of Global Approaches for Risk Assessment
Skills Development and Resources for Risk Assessment
Case Studies Chapter
Introduction
Hazard Identification
Dose-Response
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edited by David J.K. Balfour, Marcus R. Munafo
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Current Topics in Behavioral Neurosciences ; 23
オンライン: http://dx.doi.org/10.1007/978-3-319-13665-3
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edited by Irena Sherameti, Ajit Varma
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Soil Biology ; 44
オンライン: http://dx.doi.org/10.1007/978-3-319-14526-6
目次情報: 続きを見る
Sources of heavy metals in soils
Monitoring heavy metals in soils
Adaption strategies of plants and bacteria in response to heavy metals
Approaches for the remediation of contaminated soils
Genetic engineering ? a tool to cleaning up contaminated
Sources of heavy metals in soils
Monitoring heavy metals in soils
Adaption strategies of plants and bacteria in response to heavy metals
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edited by Peter Girman, Jan Kriz, Peter Balaz
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-14559-4
目次情報: 続きを見る
History of Transplantation in Animal Models
Equipment Requirments for a Experimental Laboratory
Surgical Anatomy.-Kidney
Pancreas
Liver
Heart
Small bowel
Immunosupression in Rat Models
Anesthesia in Rodent Models
Basic Surgical Techniques
Vascular anastomosis
Enteric anastomosis
Ureteral anastomosis
Biliary anastomosis
GIT anastomosis
Blood sampling ? tail vein, periorbital vein, femoral vein
Postoperative Care
Pancreas and islet transplantation
Kidney transplantation
Liver transplantation
Heart transplantation
Small bowel transplantation
Transplantation of vascular allograft
Transplantation of nervous tissue
History of Transplantation in Animal Models
Equipment Requirments for a Experimental Laboratory
Surgical Anatomy.-Kidney
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edited by Beth Okamura, Alexander Gruhl, Jerri L. Bartholomew
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-14753-6
目次情報: 続きを見る
An introduction to myxozoan evolution, ecology and development
Myxozoan affinities and route to endoparasitism
Cnidarian origins of the Myxozoa
Adaptive radiation and evolution within the Myxozoa
Classification and phylogenetics of Myxozoa
Approaches for characterizing myxozoan species
Myxozoans exploiting homeotherms
Cellular processes in myxozoans
Tissue characteristics and development in Myxozoa
Myxozoan life cycles: practical approaches and insights
Ecology and evolution of malacosporean-bryozoan interactions
Annelid-myxosporean interactions
Transmission of myxozoans to vertebrate hosts
Fish immune responses to Myxozoa
Host and environmental influences on development of disease
Specificity of infection sites in vertebrate hosts
Comparative epidemiology of myxozoan diseases
Myxozoans on the move: dispersal modes, exotic species and emerging diseases
Modeling the Effects of Climate Change on Disease Severity: A Case Study of Ceratonova (syn Ceratomyxa) shasta in the Klamath River
Risk assessments and approaches for evaluating myxozoan disease impacts
Mitigating myxozoan disease impacts on wild fish populations
An introduction to myxozoan evolution, ecology and development
Myxozoan affinities and route to endoparasitism
Cnidarian origins of the Myxozoa
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edited by Emanuele Serrelli, Nathalie Gontier
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Interdisciplinary Evolution Research ; 2
オンライン: http://dx.doi.org/10.1007/978-3-319-15045-1
目次情報: 続きを見る
Part 1: Macroevolutionary Explanations and Interpretations
Can Modern Evolutionary Theory Explain Macroevolution?
Evolution as a Largely Autonomous Process
Visualizing Macroevolution: From Adaptive Landscapes to Compositions of Multiple Spaces
Toward a Natural Philosophy of Macroevolution
Networks and Hierarchies: Approaching Complexity in Evolutionary Theory
Uniting Micro - with Macroevolution into an Extended Synthesis: Reintegrating Life’s Natural History into Evolution Studies
Part 2: Evidencing Macroevolution with Case Studies
Using Microevolution to Explain the Macroevolutionary Observations for the Evolution of Sex
Speciation: Expanding the Role of Biogeography and Niche Breadth in Macroevolutionary Theory
Morphological Misfits and the Architecture of Development
Macroevolution In and Around the Hominin Clade
Facing the Big Sixth: From Prioritizing Species to Conserving Biodiversity
Part 1: Macroevolutionary Explanations and Interpretations
Can Modern Evolutionary Theory Explain Macroevolution?
Evolution as a Largely Autonomous Process
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edited by Ulrike Boehmer, Ronit Elk
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-15057-4
目次情報: 続きを見る
Forward
Introduction
I Understanding and Reducing the Risk for Cancer
Risk for Cancer in Gay, Bisexual and Transgender Men via Infection
Understanding and Reducing Risks via Infection in LBT Women
Addressing Behavioral Cancer Risks from a LGBT Health Equity Perspective
Smoking in the LGBT Community
II Screening for Cancer in LGBT populations
Cancer screening in Lesbian and Bisexual Women and Trans Men
Cancer screening in Gay and Bisexual Men and Transgender People PART III: Cancer Survivorship
What are the numbers? Epidemiology of Cancer in the LGBT community
Breast Cancer in Lesbian and Bisexual Women
Gay Men and Prostate Cancer: Opportunities To Improve HRQOL and Access To Care
HIV-Associated Cancers
Provider-Patient Issues for the LGBT Cancer Patient
Needs of LGBT Cancer Survivors
Challenges and Recommended Solutions for Receiving Appropriate End-Of-Life-Care for Lesbians, Gay, Bisexual and Transgender Patients Diagnosed with Cancer with a Life-Limiting Prognosis
IV Cancer at the Intersection
Cancer Care needs of Transgender, Transsexual and other Gender Nonconforming Populations
The Needs of Racial/Ethnic LGBT Individuals across the Cancer Care Continuum
V Healthcare Policy and LGBT Health
Policy and its Impact on LGBT Cancer
Current policy and research on cancer in LGBT communities internationally
The Challenges Remain: Needed Next Steps in Alleviating the Burden of Cancer in the LGBT Community
Contributors
Index
Forward
Introduction
I Understanding and Reducing the Risk for Cancer
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by Ton J. Cleophas, Aeilko H. Zwinderman
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-15195-3
目次情報: 続きを見る
Preface. Section I Cluster and Classification Models
Hierarchical Clustering and K-means Clustering to Identify?Subgroups in Surveys (50 Patients)
Density-based Clustering to Identify Outlier Groups in Otherwise Homogeneous Data (50 Patients)
Two Step Clustering to Identify Subgroups and Predict Subgroup Memberships in Individual Future Patients (120 Patients)- Nearest Neighbors for Classifying New Medicines (2 New and 25 Old Opioids)- Predicting High-Risk-Bin Memberships (1445 Families)
Predicting Outlier Memberships (2000 Patients)
Data Mining for Visualization of Health Processes (150 Patients)
8?Trained Decision Trees for a More Meaningful Accuracy (150 Patients)
Typology of Medical Data (51 Patients)
Predictions from Nominal Clinical Data (450 Patients)
Predictions from Ordinal Clinical Data (450 Patients)
Assessing Relative Health Risks (3000 Subjects)
Measurement Agreements (30 Patients)
Column Proportions for Testing Differences between Outcome Scores (450 Patients)
Pivoting Trays and Tables for Improved Analysis of Multidimensional Data (450 Patients)
Online Analytical Procedure Cubes for a More Rapid Approach to?Analyzing Frequencies (450 Patients)
Restructure Data Wizard for Data Classified the Wrong Way (20 Patients)
Control Charts for Quality Control of Medicines (164 Tablet Disintegration Times)
Section II (Log) Linear Models
Linear, Logistic, and Cox Regression for Outcome Prediction with Unpaired Data (20, 55, and 60 Patients)
Generalized Linear Models for Outcome Prediction with Paired Data (100 Patients and 139 Physicians)
Generalized Linear Models for Predicting Event-Rates (50 Patients)
Factor Analysis and Partial Least Squares (PLS) for Complex-Data Reduction (250 Patients)
Optimal Scaling of High-sensitivity Analysis of Health Predictors (250 Patients)
Discriminant Analysis for Making a Diagnosis from Multiple Outcomes (45 Patients)
Weighted Least Squares for Adjusting Efficacy Data with?Inconsistent Spread (78 Patients)
Partial Correlations for Removing Interaction Effects from Efficacy Data (64 Patients)
Canonical Regression for Overall Statistics of Multivariate Data (250 Patients)
Multinomial Regression for Outcome Categories (55 Patients)
Various Methods for Analyzing Predictor Categories (60 and 30 Patients)
Random Intercept Models for Both Outcome and Predictor Categories (55 Patients)
Automatic Regression for Maximizing Linear Relationships (55 Patients)
Simulation Models for Varying Predictors (9000 Patients)
Generalized Linear Mixed Models for Outcome Prediction from Mixed Data (20 Patients)
Two Stage Least Squares for Linear Models with Problematic Predictors (35 Patients)
Autoregressive Models for Longitudinal Data (120 Monthly Population Records)
Variance Components for Assessing the Magnitude of Random Effects (40 Patients)
Ordinal Scaling for Clinical Scores with Inconsistent Intervals (900 Patients)
Loglinear Models for Assessing Incident Rates with Varying Incident Risks (12 Populations)
Loglinear Models for Outcome Categories (445 Patients)
Heterogeneity in Clinical Research: Mechanisms Responsible (20 Studies)
Performance Evaluation of Novel Diagnostic Tests (650 and 588 Patients)
Quantile - Quantile Plots, a Good Start for Looking at Your Medical Data (50 Cholesterol Measurements and 52 Patients)
Rate Analysis of Medical Data Better than Risk Analysis (52 Patients)
Trend Tests Will Be Statistically Significant if Traditional Tests Are not (30 and 106 Patients)
Doubly Multivariate Analysis of Variance for Multiple Observations from Multiple Outcome Variables (16 Patients)
Probit Models for Estimating Effective Pharmacological Treatment Dosages (14 Tests)
Interval Censored Data Analysis for Assessing Mean Time to Cancer Relapse (51 Patients)
Structural Equation Modeling with SPSS Analysis of Moment Structures (Amos) for Cause Effect Relationships I (35 Patients)
Structural Equation Modeling with SPSS Analysis of Moment Structures (Amos) for Cause Effect Relationships II (35 Patients)
Section III Rules Models
Neural Networks for Assessing Relationships that are Typically Nonlinear (90 Patients). Complex Samples Methodologies for Unbiased Sampling (9,678 Persons)
Correspondence Analysis for Identifying the Best of Multiple Treatments in Multiple Groups (217 Patients)
Decision Trees for Decision Analysis (1004 and 953 Patients).-Multidimensional Scaling for Visualizing Experienced Drug Efficacies (14 Pain-killers and 42 Patients)
Stochastic Processes for Long Term Predictions from Short Term Observations
Optimal Binning for Finding High Risk Cut-offs (1445 Families)
Conjoint Analysis for Determining the Most Appreciated Properties of Medicines to Be Developed (15 Physicians)
Item Response Modeling for Analyzing Quality of Life with Better Precision (1000 Patients)
Survival Studies with Varying Risks of Dying (50 and 60 Patients)
Fuzzy Logic for Improved Precision of Pharmacological Data Analysis (9 Induction Dosages)
Automatic Data Mining for the Best Treatment of a Disease (90 Patients)
Pareto Charts for Identifying the Main Factors of Multifactorial Outcomes (2000 Admissions to Hospital)
Radial Basis Neural Networks for Multidimensional Gaussian Data (90 persons)
Automatic Modeling for Drug Efficacy Prediction (250 Patients)
Automatic Modeling for Clinical Event Prediction (200 Patients)
Automatic Newton Modeling in Clinical Pharmacology (15 Alfentanil dosages, 15 Quinidine time-concentration relationships)
Spectral Plots for High Sensitivity Assessment of Periodicity (6 Years’ Monthly C Reactive Protein Levels)
Runs Test for Identifying Best Analysis Models (21 Estimates of Quantity and Quality of Patient Care)
Evolutionary Operations for Health Process Improvement (8 Operation Room Settings)
Bayesian Networks for Cause Effect Modeling (600 Patients)
Support Vector Machines for Imperfect Nonlinear Data
Multiple Response Sets for Visualizing Clinical Data Trends (811 Patient Visits)
Protein and DNA Sequence Mining
Iteration Methods for Crossvalidation (150 Patients)
Testing Parallel-groups with Different Sample Sizes and Variances (5 Parallel-group Studies)
Association Rules between Exposure and Outcome (50 and 60 Patients)
Confidence Intervals for Proportions and Differences in?Proportions (100 and 75 Patients)
Ratio Statistics for Efficacy Analysis of New Drugs 50 Patients)
Fifth Order Polynomes of Circadian Rhythms (1 Patient)
Gamma Distribution for Estimating the Predictors of Medical Outcomes (110 Patients) Index
Preface. Section I Cluster and Classification Models
Hierarchical Clustering and K-means Clustering to Identify?Subgroups in Surveys (50 Patients)
Density-based Clustering to Identify Outlier Groups in Otherwise Homogeneous Data (50 Patients)
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by Elizabeth A. Kellogg
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: The Families and Genera of Vascular Plants ; 13
オンライン: http://dx.doi.org/10.1007/978-3-319-15332-2
目次情報: 続きを見る
Poaceae ? General Information: Description of the family
Vegetative morphology and anatomy
Inflorescence structure
Flower structure
Embryology
Karyology and genome structure
Pollen
Fruit and seed
Distribution, habitats and conservation
Reproductive systems
Fossil record and dates of diversification
Domestication
Affinities
Classification of the Poaceae: Subdivision of the family
I. Subfamily Anomochlooideae
II. Subfamily Pharoideae
III. Subfamily Puelioideae
IV. Subfamily Ehrhartoideae
V. Subfamily Bambusoideae
VI. Subfamily Pooideae
VII. Subfamily Aristidoideae
VIII. Subfamily Panicoideae
IX. Subfamily Danthonioideae
X. Subfamily Chloridoideae
XI. Subfamily Micrairoideae
XII. Subfamily Arundinoideae. ?
Poaceae ? General Information: Description of the family
Vegetative morphology and anatomy
Inflorescence structure
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edited by Jamie C. DeWitt
出版情報: Cham : Springer International Publishing : Imprint: Humana Press, 2015
シリーズ名: Molecular and Integrative Toxicology ;
オンライン: http://dx.doi.org/10.1007/978-3-319-15518-0
目次情報: 続きを見る
Perfluorinated compounds: An overview
Analysis of PFASs in biological tissues and fluids
PFASs in the general population
PFAS Biomonitoring in Higher Exposed Populations
Perfluorinated Alkyl Acids in Wildlife
Metabolism and Pharmacokinetics
Metabolic EffectsPFAS
Developmental Toxicity
Neurotoxicity
Immunotoxicity of Perfluoroalkylated Compounds
Effects of PFOA on Endocrine-related Systems
Carcinogenicity of Perfluoroalkyl Compounds
Epidemiological Findings
Dosimetric Anchoring of Toxicological Studies
Human Health Risk Assessment of Perfluoroalkyl Acids
Systematic Review, An Illustration of Increased Transparency in a Framework for Evaluating Immunotoxicity Associated with PFOA and PFOS Exposure
Toxicology data for alternative “short-chain” fluorinated substances
Conclusions and recommendations.??
Perfluorinated compounds: An overview
Analysis of PFASs in biological tissues and fluids
PFASs in the general population
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edited by Kathleen M. Kantak, Joseph G. Wettstein
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Handbook of Experimental Pharmacology ; 228
オンライン: http://dx.doi.org/10.1007/978-3-319-16522-6
目次情報: 続きを見る
Preface
Part?1. Basic Approaches and?Perspectives
Part?2. Cognitive Domains for Pharmacological Intervention: Implications for Neuropsychiatric and Neurological Illnesses
Part 3. Developmental Disorders, Emerging Technologies and Ethical Considerations
Preface
Part?1. Basic Approaches and?Perspectives
Part?2. Cognitive Domains for Pharmacological Intervention: Implications for Neuropsychiatric and Neurological Illnesses
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by Avraham Mayevsky
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-16682-7
目次情報: 続きを見る
1. Introduction
2. Tissue Energy Metabolism and Mitochondrial Function
3. Spectroscopic monitoring of NADH ? Historical Overview
4. Technological aspects of NADH monitoring In Vivo
5. Monitoring of NADH together with other tissue physiological parameters
6. Multisite Monitoring of NADH
7. Responses of NADH to physiological and pathophysiological conditions
8. Monitoring of various organs in various animal models
9. Monitoring of NADH in Human brain and body organs
10. Discussion
Index
1. Introduction
2. Tissue Energy Metabolism and Mitochondrial Function
3. Spectroscopic monitoring of NADH ? Historical Overview
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edited by Mieczyslaw Pokorski
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Advances in Experimental Medicine and Biology ; 852
オンライン: http://dx.doi.org/10.1007/978-3-319-16922-4
目次情報: 続きを見る
The Role of Mediastinoscopy in the Diagnosis of Thoracic disease: One-Year Single Center Experience, M. Chabowski, A. Szymanska-Chabowska, J. Skotarczak, D. Janczak Jr, L. Pawlowski, and D. Janczak
Shoulder Ring Complaints as a Rare First Symptom of Malignant Pleural Mesothelioma, J. Lorkowski, O. Grzegorowska, A. Kotela, W. Wery?ski, and I. Kotela
Primary Prosthetic Voice Rehabilitation in Patients after Laryngectomy: Applications and Pitfalls, V. Calkovsky and A. Hajtman
A Unilateral Hemothorax as a Presenting Manifestation of Mediastinal Spindle Cell Sarcoma, M. Chabowski, A. Szymanska-Chabowska, M. Szolkowska, and D. Janczak
Diagnostic Performance of Different Pleural Fluid Biomarkers in Tuberculous Pleurisy, J. Klimiuk, R. Krenke, A. Safianowska, P. Korczynski, and R. Chazan
Low-Dose Computer Tomography as a Screening Tool for Lung Cancer in a High Risk Population
A. Nahorecki, M. Chabowski, T. Ku?niar, B. K?dzierski, P. Ja?wiec, A. Szuba, and D. Janczak
Decreased FAM107A Expression in Patients with Non-Small Cell Lung Cancer, D. Pastuszak-Lewandoska, K.H. Czarnecka, M. Migdalska-S?k, E. Nawrot, D. Doma?ska, J. Kisza?kiewicz, J. Kordiak, A. Antczak, P. Gorski, and E. Brzezia?ska-Lasota
Clinical Significance of HMGB-1 and TGF-β Level in Serum and BALF of Advanced Non-Small Cell Lung Cancer, K. Jakubowska, W. Naumnik, W. Nikli?ska, and E. Chyczewska
TGF-β and SMADs mRNA Expression in Pulmonary Sarcoidosis
W.J. Piotrowski, J. Kisza?kiewicz, D. Pastuszak-Lewandoska, A. Antczak, P. Gorski , M. Migdalska-S?k, W. Gorski,?K. Czarnecka, E. Nawrot, D. Doma?ska, E. Brzezia?ska-Lasota
The Role of Mediastinoscopy in the Diagnosis of Thoracic disease: One-Year Single Center Experience, M. Chabowski, A. Szymanska-Chabowska, J. Skotarczak, D. Janczak Jr, L. Pawlowski, and D. Janczak
Shoulder Ring Complaints as a Rare First Symptom of Malignant Pleural Mesothelioma, J. Lorkowski, O. Grzegorowska, A. Kotela, W. Wery?ski, and I. Kotela
Primary Prosthetic Voice Rehabilitation in Patients after Laryngectomy: Applications and Pitfalls, V. Calkovsky and A. Hajtman
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edited by Olga Gursky
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Advances in Experimental Medicine and Biology ; 855
オンライン: http://dx.doi.org/10.1007/978-3-319-17344-3
目次情報: 続きを見る
Role of Lipids in Folding, Misfolding and Function of Integral Membrane Proteins
Protein?Misfolding in Lipid-Mimetic Environments
Lipids in Amyloid-β Processing, Aggregation, and Toxicity
Role of Cholesterol and Phospholipids in Amylin Misfolding, Aggregation and Etiology of Islet Amyloidosis
Stability, Oligomerization, and Amyloidogenicity of Apo Serum Amyloid A
Interactions of Lipid Membranes with Fibrillar Protein Aggregates
The Role of Lipid in Misfolding and Amyloid Fibril Formation by Apolipoprotein C-II
Amyloid-Forming Properties of Human Apolipoproteins: Sequence Analyses and Structural Insights
Computational Approaches to Identification of Aggregation Sites and the Mechanism of Amyloid Growth
Role of Syndecans in Lipid Metabolism and Human Diseases
Role of Lipids in Folding, Misfolding and Function of Integral Membrane Proteins
Protein?Misfolding in Lipid-Mimetic Environments
Lipids in Amyloid-β Processing, Aggregation, and Toxicity
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by Georgi Muskhelishvili
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: SpringerBriefs in Biochemistry and Molecular Biology ;
オンライン: http://dx.doi.org/10.1007/978-3-319-17425-9
目次情報: 続きを見る
Introduction: Some facts about our Universe
Problems of logical typing: The "one" and the "unity"
Logical typing and the notion of time in biology
Organisation of the genetic system: Proteins as vehicles of distinction
Harnessing energy and information: Time-irreversibility of thermodynamics
Social communications and logical typing in the social system
Introduction: Some facts about our Universe
Problems of logical typing: The "one" and the "unity"
Logical typing and the notion of time in biology
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edited by Benjamin Bonavida, Salem Chouaib
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Resistance to Targeted Anti-Cancer Therapeutics ; 7
オンライン: http://dx.doi.org/10.1007/978-3-319-17807-3
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edited by Maria Cristina Galli, Mercedes Serabian
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Advances in Experimental Medicine and Biology ; 871
オンライン: http://dx.doi.org/10.1007/978-3-319-18618-4
目次情報: 続きを見る
1. Regulatory Oversight of Gene Therapy and Cell Therapy Products in the US - FDA/CBER
2. US Oversight of Gene Therapy Products ? NIH RAC
3. Regulatory Oversight of Gene Therapy and Cell Therapy Products in Canada - Health Canada
4. Overview of the Regulatory Oversight Implemented by the French Regulatory Authorities for the Clinical Investigation of Gene Therapy and Cell Therapy Products
5. Regulation of Clinical Trials with Advanced Therapy Medicinal Products (ATMP) in Germany
6. EU Clinical Trials Regulatory Oversight of Advanced Therapy Medicinal Products (ATMP): Perspectives from Various Member States
7. Regulatory Oversight of Gene Therapy and Cell Therapy Products in Switzerland - Swissmedic
8. Regulatory Oversight of Gene Therapy and Cell Therapy Products in Japan - Japan Ministry of Health, Labour and Welfare (MHLW) and Pharmaceutical and Medical Device Agency (PMDA)
9. Regulatory Oversight of Gene Therapy and Cell Therapy Products in Korea - Korean Ministry of Food and Drug Safety (MFDS)
10. Regulatory Oversight of Gene Therapy and Cell Therapy Products in Taiwan - Taiwan Food and Drug Administration (TFDA)
11. Regulatory Oversight of Gene Therapy and Cell Therapy Products in Singapore - Singapore Health Science Authorities (HSA)
12. Regulatory Oversight of Gene Therapy and Cell Therapy Products in Brazil - National Health Surveillance Agency (ANVISA)
1. Regulatory Oversight of Gene Therapy and Cell Therapy Products in the US - FDA/CBER
2. US Oversight of Gene Therapy Products ? NIH RAC
3. Regulatory Oversight of Gene Therapy and Cell Therapy Products in Canada - Health Canada
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edited by Richard Bronson
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Advances in Experimental Medicine and Biology ; 868
オンライン: http://dx.doi.org/10.1007/978-3-319-18881-2
目次情報: 続きを見る
Preface
Meiotic Non-disjunction - Insights into the Origin and Significance of Aneuploidy in Human Spermatozoa
Damage to Sperm DNA Mediated by Reactive Oxygen Species: Its Impact on Human Reproduction and the Health Trajectory of Offspring
Small RNAs: Their Possible Roles in Reproductive Failure
The Sperm Epigenome, Male Aging and Potential Effects on the Embryo
The Role of Uterine NK Cells in Normal Reproduction and Reproductive Disorders
Seminal fluid Signaling in the Female Reproductive Tract: Implications for Reproductive Success and Offspring Health
Role of Seminal Plasma in Human Female Reproductive Failure:? Immunomodulation, Inflammation and Infections
Human Leukocyte Antigen-G Within the Male Reproductive System - Implications for Reproduction
Prostasomes - Their Characterization: Implications for Human Reproduction
The Paternal Contribution to Fetal Tolerance
Index
Preface
Meiotic Non-disjunction - Insights into the Origin and Significance of Aneuploidy in Human Spermatozoa
Damage to Sperm DNA Mediated by Reactive Oxygen Species: Its Impact on Human Reproduction and the Health Trajectory of Offspring
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edited by Kakoli Bose
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-19497-4
目次情報: 続きを見る
Apoptosis: Pathways, Molecules and Beyond
Caspases - key players in apoptosis
Calpains and Granzymes: non-caspase proteases in cell death
Cathepsins and HtrAs - multitasking proteases in programmed cell death
Proteases in Apoptosis: Protocols and Methods
Preclinical Animal Model and Non-invasive Imaging in Apoptosis
Apoptosis: Pathways, Molecules and Beyond
Caspases - key players in apoptosis
Calpains and Granzymes: non-caspase proteases in cell death
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edited by Ulysses Paulino Albuquerque, Patricia Muniz De Medeiros, Alejandro Casas
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-19917-7
目次情報: 続きを見る
Evolutionary Ethnobiology
Ecological-evolutionary Approaches to the Human-environment Relationship: History and Concepts
Evolution of Humans and by Humans
Evolutionary Ecology and Ethnobiology
Evolutionary Approaches to Ethnobiology
Niche Construction Theory and Ethnobiology
Knowledge Transmission: The Social Origin of Information and Cultural Evolution
Resilience and Adaptation in Social-ecological Systems
Utilitarian Redundancy: Conceptualization and Potential Applications in Ethnobiological Research
The Influence of the Environment on Natural Resource Use: Evidence of Apparency
Local Criteria for Medicinal Plant Selection
Use Patterns of Medicinal Plants by Local Populations
Biological and Cultural Bases of the Use of Medicinal and Food Plants
An Evolutionary Perspective on the Use of Hallucinogens
Evolutionary Ethnobiology
Ecological-evolutionary Approaches to the Human-environment Relationship: History and Concepts
Evolution of Humans and by Humans
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edited by Natalya Kurochkina
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-20098-9
目次情報: 続きを見る
SH3 Domains as Suitable Models to Study Amyloid Aggregation
SH Domain Proteins in Plants: Roles in Signaling Transduction and Membrane Trafficking
Versatility of SH3 Domains in the Cellular Machinery
Structure-Function Relationship of Bacterial SH3 Domains
Activation of PI3K by Thyroid Hormone Nuclear Receptors
SH Domains’ Interaction with SliMs: Maximizing Adaptivity of Signaling Networks
SH Domains and Epidermal Growth Factor Receptor
SH2 Domain Structures and Interactions
Cytoskeletal Signaling by Src Homology Domain-Containing Adaptor Proteins
Structure and Function of Jak3- SH2 Domain
Helical Assemblies and SH Domains
SH3 Domains as Suitable Models to Study Amyloid Aggregation
SH Domain Proteins in Plants: Roles in Signaling Transduction and Membrane Trafficking
Versatility of SH3 Domains in the Cellular Machinery
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edited by Micaela Morelli, Nicola Simola, Jadwiga Wardas
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Current Topics in Neurotoxicity ; 10
オンライン: http://dx.doi.org/10.1007/978-3-319-20273-0
目次情報: 続きを見る
Adenosine A2A receptors: localization and function
Allosteric Mechanisms in the adenosine A2A-dopamine D2 receptor heteromer
Adenosine A2A receptor antagonists in drug development
Adenosine A2A Receptors and Neurotrophic Factors: Relevance for Parkinson's Disease
Role of adenosine A2A receptors in the control of neuroinflammation ? relevance for Parkinson’s disease
Purines in Parkinson's: Adenosine A2A receptors and urate as targets for neuroprotection
Adenosine A2A receptor antagonists as drugs for symptomatic control of Parkinson’s disease in preclinical studies
Dopamine/adenosine interactions related to tremor in animal models of Parkinsonism
Adenosine A2A receptor antagonists in L-DOPA-induced motor fluctuations
Adenosine A2A receptor-mediated control of non-motor functions in Parkinson’s disease
Imaging Studies with A2A Receptor Antagonists
Caffeine and neuroprotection in Parkinson's disease
The story of istradefylline ? the first approved A2A antagonist for the treatment of Parkinson’s disease
Adenosinergic Receptor Antagonists: Clinical Experience in Parkinson's Disease
Adenosinergic regulation of sleep-wake behavior in the basal ganglia
Adenosine A2A receptors: localization and function
Allosteric Mechanisms in the adenosine A2A-dopamine D2 receptor heteromer
Adenosine A2A receptor antagonists in drug development
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edited by Arunika N. Gunawardena, Paul F. McCabe
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
オンライン: http://dx.doi.org/10.1007/978-3-319-21033-9
目次情報: 続きを見る
An Overview of Programmed Cell Death Research: From Canonical to Emerging Model Species
Mitochondrion and Chloroplast Regulation of Plant Programmed Cell Death
Life Beyond Death: the Formation of Xylem Sap Conduits
Programmed Cell Death in Plant Immunity: Cellular Reorganization, Signaling and Cell Cycle Dependence in Cultured Cells as a Model System
Vascular Aerenchyma and PCD
Out for a Walk Along the Secretory Pathway During Programmed Cell Death
Nuclear Dismantling Events: Crucial Steps During the Execution of Plant Programmed Cell Death
Programmed Cell Death Regulation by Plant Proteases with Caspase-Like Activity
Senescence-Associated Programmed Cell Death
The Hypersensitive Response in PAMP- and Effector-Triggered Immune Responses
To Live or Die: Auophagy in Plants
An Overview of Programmed Cell Death Research: From Canonical to Emerging Model Species
Mitochondrion and Chloroplast Regulation of Plant Programmed Cell Death
Life Beyond Death: the Formation of Xylem Sap Conduits
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edited by Ivan Bertoncello
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Stem Cell Biology and Regenerative Medicine ;
オンライン: http://dx.doi.org/10.1007/978-3-319-21082-7
目次情報: 続きを見る
Part 1. Fetal Lung Development
The Regulation of Branching Morphogenesis in the Developing Lung
Epithelial-Mesenchymal Crosstalk in Lung Development
Lung Vasculogenesis and Angiogenesis
Neural Regulation of Lung Development
Fetal and Neonatal Origins of Lung Disease
Part 2. Adult Lung Stem and Progenitor Cells
Stem and Progenitor Cells of the Trachea and Proximal Airways
Stem and Progenitor Cells of the Distal Bronchiolar Airways
Regenerative Cells in the Ageing Lung
Part 3. Regulation of Lung Regeneration and Repair
Stromal Regulation of Lung Regeneration and Repair
Immunomodulatory Regulation Of Lung Regeneration and Repair
Extracellular Matrix Specification of Regenerative Cells in the Adult Lung
Role of Mechanical Stress in Lung Repair and Regeneration
Part 4. Cellular Therapies for Lung Disease
Cellular Origins of Fibrotic Lung Diseases
Mesenchymal Stromal Cell Based Therapies for Lung Disease
Lung Vascular Regeneration and Repair
Directed Differentiation of Human Pluripotent Stem Cells into Lung and Airway Epithelial Cells
Part 5. Bioengineering the Lung
Regenerating the Respiratory Tract
Acellular Lung Scaffolds in Lung Bioengineering
Part 6. Afterword.-Prospects and Challenges in Lung Regenerative Medicine
Part 1. Fetal Lung Development
The Regulation of Branching Morphogenesis in the Developing Lung
Epithelial-Mesenchymal Crosstalk in Lung Development
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edited by Tanya E. S. Dahms, Kirk J. Czymmek
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Fungal Biology ;
オンライン: http://dx.doi.org/10.1007/978-3-319-22437-4
目次情報: 続きを見る
Applications of Confocal Laser Scanning Microscopy in Filamentous Fungi
Fluorescence-based Methods for the Study of Protein Localization, Interaction, and Dynamics in Filamentous Fungi
Super Resolution Microscopy: SIM, STED and Localization Microscopy
Fourier Transform Infrared (FTIR) Microscopy and Imaging of Fungi
Whole Cells Imaged by Hard X-ray Transmission Microscopy
In situ Nanocharacterization of Yeast Cells Using ESEM and FIB
Imaging Living Yeasts Cells and Quantifying Their Biophysical Properties by Atomic Force Microscopy
Future Directions in Mycological Microscopy
Applications of Confocal Laser Scanning Microscopy in Filamentous Fungi
Fluorescence-based Methods for the Study of Protein Localization, Interaction, and Dynamics in Filamentous Fungi
Super Resolution Microscopy: SIM, STED and Localization Microscopy
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edited by Dinesh K. Maheshwari
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: Sustainable Development and Biodiversity ; 12
オンライン: http://dx.doi.org/10.1007/978-3-319-24654-3
目次情報: 続きを見る
Techniques to study Microbial phytohormones
Azospirillum sp. as a challenge for agriculture
Emergence of Methylobacterium spp. as potential organism in Agriecosystems
Role of bacterial phytohormones in plant growth regulation and their development
Soil bacteria and phytohormones for sustainable crop production
The Importance of Phytohormones and Microbes as Biofertilizers
Phytohormone producing PGPR for Sustainable Agriculture
Indole-3-Acetic Acid? and 1-Aminocyclopropane-1-Carboxylate Deaminase: Bacterial traits required in rhizosphere,rhizoplane and/or endophytic competence by beneficial bacteria
Role of Abscisic acid producing PGPR in sustainable agriculture
Microbial phytohormones have a key role in mitigating the salt-induced damages in plants
Exploitation of phytohormone producing PGPR in development of multispecies bioinoculant formulation
Significance of Biosurfactants as antibiofilm agents in eradicating phytopathogens
Biofilm formation and biosurfactant activity in plant-associated bacteria
Bioremediation? strategies employed by Pseudomonas species
Techniques to study Microbial phytohormones
Azospirillum sp. as a challenge for agriculture
Emergence of Methylobacterium spp. as potential organism in Agriecosystems
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by Muhammad Aslam, Muhammad Amir Maqbool, Rahime Cengiz
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: SpringerBriefs in Agriculture ;
オンライン: http://dx.doi.org/10.1007/978-3-319-25442-5
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by Peter Bross
出版情報: Cham : Springer International Publishing : Imprint: Springer, 2015
シリーズ名: SpringerBriefs in Molecular Science ;
オンライン: http://dx.doi.org/10.1007/978-3-319-26088-4
目次情報: 続きを見る
Introduction
Historical sketch of the discovery and recognition of the function of chaperonins
Molecular structure of chaperonins
Folding by enclosure in the chaperonin cavity
Evolutionary origins and family relations
Chaperoning mechanisms: folding helpers, folding protectors or misfolding blockers?
Sequence variations in proteins affecting chaperonin dependence
Genetic organization of type I chaperonin genes
Regulation of type I chaperonin gene expression
Subcellular localization
Posttranslational modifications
Variations in Hsp60 and Hsp10 in humans
Type I chaperonins are essential for cell viability and mutations cause deficiency phenotypes
Human diseases caused by genetic mutations in the Hsp60/Hsp10 system
Molecular investigations of disease mechanisms
Outlook
Introduction
Historical sketch of the discovery and recognition of the function of chaperonins
Molecular structure of chaperonins
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by Grischa Brokamp
出版情報: Wiesbaden : Springer Fachmedien Wiesbaden : Imprint: Springer Spektrum, 2015
オンライン: http://dx.doi.org/10.1007/978-3-658-08696-1
目次情報: 続きを見る
Standardized Data Collection on Trade in Palm Products
Trade in Palm Products in North-Western South America
Case study on Productivity and Management of Phytelephas aequatorialis (Arecaceae) in Ecuador
Parasitism and Haustorium Anatomy of Krameria lappacea (Krameriaceae), an Endangered Medicinal Plant from the Andean Deserts
Abundance, Seed Ecology and Regeneration of Krameria lappacea from the Peruvian Andes
Standardized Data Collection on Trade in Palm Products
Trade in Palm Products in North-Western South America
Case study on Productivity and Management of Phytelephas aequatorialis (Arecaceae) in Ecuador